Input gene set

Try a gene set example.

Or search for mimickers and reversers:

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generated by the Library of Integrated Network-based Cellular Signatures

(LINCS) program to find the most similar gene sets that match your query.

L2S2 includes over 1.4 million chemical perturbation and over 280,000 CRISPR knockout signatures.

Please acknowledge L2S2 in your publications by citing the following reference:

Giacomo B Marino, John E Evangelista, Daniel J B Clarke, Avi Ma'ayan,

L2S2: chemical perturbation and CRISPR KO LINCS L1000 signature search engine.

Nucleic Acids Res, 2025; gkaf373, https://doi.org/10.1093/nar/gkaf373